产品货号：
Z36788
中文名称：
PARL抗体
英文名称：
Anti-PARL Antibody (Clone#8C4B2/1H12E10)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PARL Antibody (Clone#8C4B2/1H12E10) |
| 指标别名 | MAMP;PACT;PARL;Pbeta;PRO2207;PSARL;PSARL1;PSENIP2;RHBDS1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,ELISA |
| 基因名称 | PARL |
| 克隆号 | 8C4B2/1H12E10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Purified recombinant fragment of PARL (aa112-167) expressed in E.Coli. |
| 计算分子量 | 42KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | PARL is a mitochondrial integral membrane protein and a member of the highly conserved rhomboid superfamily of membrane proteins.PARL is required for the control of apoptosis during postnatal growth and is required for the processing of OPA1,a protein that prevents the release of cytochrome C from the mitochondria in response to apoptotic signals.In lymphocytes and neurons,PARL's association with other proteins,such as the Bcl-2 family-related protein Hax1 and Omi can lead to the proteolytic processing of Omi by PARL,preventing the accumulation of Bax,thereby suppressing apoptosis.Variations in this gene have been associated with increased risk for type 2 diabetes.PARL may also play a role in the progression of Alzheimer's disease through its associations with presenilin-1 and -2.Multiple isoforms of PARL are known to exist. |
| Uniprot ID | Q9H300 |
| 基因名全称 | Presenilins-associated rhomboid-like protein,mitochondrial |
| 蛋白名全称 | Presenilins-associated rhomboid-like protein,mitochondrial |
| 推荐稀释比 | WB 1:500～1:2000 ELISA 1:10000 |
相关搜索：PARL抗体，PARL单抗，Anti-PARL Antibody (Clone#8C4B2/1H12E10)